Majmundar Lab Contact Us!

Amar J. Majmundar MD PhD | Principal Investigator | 2020-present

Dr. Majmundar began his medical and graduate training in the Combined Degree and Medical Scientist Training Programs at the University of Pennsylvania School of Medicine (2004-2013). There, he earned a PhD in Cell and Molecular Biology in the laboratory of M. Celeste Simon PhD. Using multiple conditional mouse models and muscle progenitor culture models, he discovered that the oxygen sensing factor Hif1α specifically regulates adult skeletal muscle regeneration, but not embryonic muscle development, by inhibiting WNT signaling.

He, subsequently, completed pediatrics training in the Boston Combined Pediatrics Residency program at Boston Children’s Hospital (BCH) and Boston Medical Center followed by pediatric nephrology fellowship training at Boston Children’s Hospital. He conducted post-doctoral fellowship research with Dr. Friedhelm Hildebrandt. Using exome sequencing, he discovered novel genetic causes of steroid-resistant nephrotic syndrome/focal segmental glomerulosclerosis (SRNS/FSGS) in human NOS1AP and TRIM8 variants. He investigated the pathogenesis of these human mutations by using podocyte cell culture and generating a novel murine knockout model of nephrotic syndrome. He further explored the Mendelian genetic landscape of pediatric and adult nephrolithiasis using gene panel and exome sequencing techniques. In the process, he determined that dominant OXGR1 variants are a potentially novel cause of nephrolithiasis. 

After completing his training, Dr. Majmundar initiated an independent basic/translational research laboratory focused on identifying novel genetic causes of human kidney disease and delineating the mechanisms of these diseases via genomics, cell systems, and mouse models. In parallel, he has co-initiated a kidney genetics clinic at BCH. 

Vineeta Sharma, PhD | Post-doctoral fellow | 2021-present

Vineeta completed her PhD degree from Indian Institute of Technology, Madras, India in Stem Cells and Molecular Biology. During PhD, her research centered on scaffold based cardiac tissue regeneration in rat myocardial infarction (MI) model. Currently I am working as post-doctoral research fellow at the Boston Children's Hospital. While working as post-doctoral fellow I will explore the underlying mechanisms of monogenic forms of steroid resistant nephrotic syndrome/focal segmental glomerulosclerosis (SRNS/FSGS). I will be focusing on generating Trim8 knockout mouse model for better understanding of disease mechanisms and utilize various cell based, molecular biology and genomic based experiments to further validate the outcomes. Outside work, Vineeta Loves cooking and painting.

Victoria Gauntner, BA | Research Assistant | 2022-present

Victoria is a recent graduate of Boston University, receiving her Bachelor's in Biology with a Specialization in Cell Biology, Molecular Biology, and Genetics. During her undergraduate career, she contributed to research on NF-kB in the Gilmore lab through her Molecular Biology Lab course and worked under Dr. Flynn to research the Alternative Lengthening of Telomeres pathway. In the Majmundar Lab, Victoria is working on protein interaction studies of the human disease protein NOS1AP and is investigating the role of genetic mutations that cause kidney stones.

Sunwoo Hong, BS | Master’s Thesis Student | 2023-present

Sunwoo graduated from University of Illinois Urbana-Champaign in 2019, where he double majored in Molecular Cellular Biology and Psychology, with a concentration in Neuroscience. After graduation, he worked as an EMT-B in New York State until the summer of 2022. Shortly after, he started his program in MS of Medical Sciences at Boston University. At the Majmundar Lab, he is currently studying the contribution of TRIM8 in the pathogenesis nephrotic syndrome. In his free time, Sunwoo enjoys going to concerts and trying out new food. 

Former Lab Members

Lorrin Liang, BS MS | 2021-2022 | Master’s Thesis Student 
  • Next Step after Lab: Medical Student at Boston University Chobanian and Avedisian School of Medicine, Class of 2026.
  • Her previous work includes contributions as a thesis student in the Majmundar Lab at Boston Children's Hospital, clinical research coordinator at the Yale Center for Clinical Investigation, and caregiver at Allied Health Services. Regarding community involvement, she currently volunteers as a mentor with The Valedictorian Project for young adults interested in pursuing a career in the medical field and has served as Director of Events for the nonprofit United Against Inequities in Disease. She also has previously been awarded a merit scholarship for her graduate studies with Boston University and amusingly voted by her peers with the superlative, "Most Likely to Be Voted Doctor Of The Year in an In-Flight Magazine." In her free time, she enjoys hiking, basketball, baking, and trying new food. She attributes her first years in Boston to be so fun and exciting thanks to her time with the Majmundar Lab and is thrilled to be able to regard her colleagues as family.

Gabrielle Wilson | 2022 | Undergraduate Student
  • Next Step after Lab: Undergraduate at Wentworth Institute of Technology
  • Gabby helped with investigations into NOS1AP interaction partners as part of her co-opt program. 

Alexander Rubin, BS, MS | Master’s Thesis Student | 2022-2023
  • Alex successfully completed his master's thesis on Trim8 research. 
  • Next Step after Lab: Medical Student at Boston University Chobanian and Avedisian School of Medicine, Class of 2027.

David Ball, BS | Research Assistant | 2020-2023
  • David was amazingly productive during his time in the lab. He identified a novel interactor of a kidney disease gene, which is part of a first author manuscript in preparation. He also presented posters at the 2021 and 2022 American Society of Nephrology Kidney Week Conferences and was selected for the competitive Kidney STARS program at Kidney Week 2022. 
  • Next Step after Lab: He is transitioning to a neural stem cell laboratory to explore his interest in stem cell research before applying for PhD programs in the biomedical sciences.